The biggest slice of cake can also be referred to as the largest portion or the most generous serving. Other synonyms for the phrase may include the largest piece, the whopping slice, the giant wedge, or the hefty portion. In some cases, it may also be described simply as the largest portion available. These variations may be used depending on the context or the tone of the conversation. Regardless of the phrasing, it is clear that everyone wants to get their hands on the biggest slice of cake available!